APERC Statement
Newly Published Weight of Evidence Manuscript
Supports US EPA Proposed Criteria for NP
April 19, 2005

A recently published manuscript¹ in the Human and Ecological Risk Assessment journal provided a weight of evidence hazard assessment using a robust statistical technique known as Species Sensitivities Distribution (SSD). About 90 chronic toxicity values from high quality peer-reviewed studies were evaluated. Using the SSD analysis for nonylphenol (NP) the authors calculated a chronic safe level of 5.7 ug/L, which supports the draft US EPA criteria for NP of 5.9 ug/L.

To obtain reprints of the manuscript please contact APERC at info@aperc.org.

¹ Staples, C., Mihaich, E., Carbone, J., Woodburn, K., and Klecka, G. (2004). A Weight of Evidence Analysis of the Chronic Ecotoxicity of Nonylphenol Ethoxylates, Nonylphenol Ether Carboxylates, and Nonylphenol. Human and Ecological Risk Assessment, 10, 999-1017.

Last updated: April 20, 2005